Herbs, epiphytic, rarely lithophytic, cespitose. Roots fleshy, glabrous. Stems erect, repent, or hanging, canelike, simple or branching. Leaves alternate; petiole tubular, sheathing, articulate; blade ovate to elliptic or lanceolate, fleshy-leathery. Inflorescences terminal [lateral or basal], racemose to nearly corymbose or distichous, producing flowers only once, or during several years from same or new racemes from old axis; flowers pedicellate or not. Flowers resupinate or not, if not then distichous or spirally arranged, simultaneous or successive; sepals nearly equal; lip adnate to column throughout, forming nectary tube, tube penetrating ovary, occasionally producing nectar; column straight or slightly arched; clinandrium hood partly covering anther; anther 4-celled; pollinia 4, obovoid, laterally compressed, nearly equal; rostellum slit, producing semiliquid viscidium attached to caudicles of pollinarium. Fruits capsules, ellipsoid to subglobose, sometimes with pedicel or beak, 3-ribbed, 1-locular.
For a description of species occurring in Australia, see Epidendrum ibaguense and Epidendrum radicans.